National Academies of Sciences%2c Engineering%2c and Medicine

Computer Assisted Modeling: Contributions of Computational Approaches to Elucidating Macromolecular Structure and Function

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Nature

Cell type-specific functions of the PBAF chromatin-remodeling complex in neuronal diversification

Mutations in two highly related chromatin-remodeling complexes, BRG1/BRM-associated factor (BAF) and Polybromo-associated BAF (PBAF), cause various neurodevelopmental conditions. Although BAF activity ...
Nature

Structure and interactions of the endogenous human Commander complex

The Commander complex, a 16-protein assembly, plays multiple roles in cell homeostasis, cell cycle and immune response. It consists of copper-metabolism Murr1 domain proteins (COMMD1–10), coiled-coil ...